Acute disseminated encephalomyelitis, multiphasic disseminated encephalomyelitis and multiple sclerosis in children. doi: 10.1212/wnl.ĭale RC, de Sousa C, Chong WK et al. Acute disseminated encephalomyelitis: a long-term follow-up study of 84 pediatric patients. Clinical study of childhood acute disseminated encephalomyelitis, multiple sclerosis, and acute transverse myelitis in Fukuoka Prefecture, Japan. Torisu H, Kira R, Ishizaki Y, Sanefuji M, Yamaguchi Y, Yasumoto S, et al. Inflammatory demyelinating diseases of the central nervous system. Acute disseminated encephalomyelitis: prognostic value of early follow-up brain MRI. Koelman D, Benkeser D, Klein J, Mateen F. Acute disseminated encephalomyelitis: current knowledge and open questions. Pediatric central nervous system demyelinating diseases. Childhood acute disseminated encephalomyelitis: an Egyptian pilot study. Acute disseminated encephalomyelitis: A clinical and neuroradiological profile of pediatric patients. Giri PP, Bhattyacharya S, Das D, Mukhopadhaya S. Acute disseminated encephalomyelitis in 228 patients. Koelman D, Chahin S, Mar S, Venkatesan A, Hoganson G, Yeshokumar A, et al. Early recognition and treatment of acute disseminated encephalomyelitis in pediatrics: a case series. George T, Basin A, Avva U, Taylor M, Muhammed J, Ogedegbe C. Acute disseminated encephalomyelitis: current controversies in diagnosis and outcome. Diagnosis and therapy of acute disseminated encephalomyelitis and its variants. Paliwal VK Acute disseminated encephalomyelitis in children. Pohl D, Alper G, Van Haren K, Kornberg A, Lucchinetti C, Tenembaum S, et al. In the 18-month follow-up, the patient has not presented new clinical or radiological events.ĪDEM, is an infrequent pathology in pediatric age, with a diagnosis based on the clinic and magnetic resonance imaging findings, its clinical presentation may be nonspecific and as in this case simulate cerebrovascular disease, the treatment is based on immunomodulatory treatment, mainly corticosteroids, with a favorable recovery rate in the previously reported series. Considering that lesions do not suggest changes of ischemic origin, but if they are demyelinating, management with methylprednisolone pulses with resolution of hemiparesis and encephalopathy is initiated. A contrast-enhanced brain resonance study with evidence of hyperintense lesions at the level of the stem, cerebellum, and basal ganglia, asymmetric, unilateral, acute, following the vascular path of the posteroinferior cerebellar artery (PICA), but without restriction to diffusion or changes on the ADC map, so that an initial suspicion of cerebrovascular event (CVD) is made, studying with normal angioresonance, diagnostic aids for negative cardioembolic causes and thrombophilias. To describe and review the clinical presentation of a patient with ADEM, its diagnostic process and therapeutic management according to the available evidence.Ī 17-year-old male adolescent, with a 2-week history of high-intensity right-sided headache, stitching type, subsequent acute multifocal neurological compromise with encephalopathy, hemiparesis, and diplopia. Acute disseminated encephalomyelitis (ADEM) is a low-prevalence demyelinating disease of the central nervous system (CNS) with a predominance of presentation in the pediatric population.
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